Serlopitant For Prurigo Nodularis Completes Phase 2 Clinical Trial

A new treatment for prurigo nodularis  is coming down the drug development pipeline. Prurigo nodularis is marked by persistent itching, stinging and burning sensation in the skin, resulting in a chronic itch-scratch cycle and resulting nodules where the skin is picked and scratched. In a phase 2 clinical trial, serlopitant, a neurokinin-1 receptor antagonist that… Read More

Sebacia Approved For Acne Treatment

Sebacia Microparticles, a novel treatment for acne was recently approved by the U.S. FDA. Sebacia is a microparticle that is applied to and massaged into the skin, where it selectively concentrates in sebaceous glands. The excess is wiped off. Following this, a 1,064 nm laser, such as an Nd:YAG laser, is applied, which results in… Read More

Cosmetic Procedures After Isotretinoin For Acne

Many patient who have been on isotretinoin for acne want to receive treatments for scarring, or other cosmetic procedures while on, or shortly after completing, a course of isotretinoin. The conventional wisdom has been that most procedures should be delayed six months after completing the isotretinoin. However, two consensus statements published in 2017, one from… Read More

Bryhali Lotion (Halobetasol Propionate), 0.01% For Psoriasis

Bryhali lotion, a form of halobetasol propionate, was recently approved by the FDA for the treatment of plaque psoriasis. Bryhali is a superpotent topical steroid, also known as a Class I steroid. Other forms of generic halobetasol propionate are available, as well as a branded product called Ultravate. Generally, the use of superpotent topical steroids… Read More

Curcumin For Psoriasis

Curcumin is derived from turmeric spice, and has been used in traditional Chinese medicine for centuries. It has been shown in some studies to be of benefit in treating psoriasis in both topical and oral formulations. In one study, a 1% curcumin gel was compared with calcipotriol. The efficacy was found to be similar between… Read More

Indigo Naturalis for Psoriasis

Many patients seek complementary or alternative medications for psoriasis. One interesting natural ingredient is indigo naturalis, which has been used in traditional Chinese medicine for hundreds of years. Indigo naturalis is derived from plants such as Baphicacanthus cusia; this is the same plant that gives rise to indigo dyes. The active element is thought to be indirubin.… Read More

Altreno (Tretinoin Lotion) For Acne

Altreno, a new form of tretinoin was recently approved for the treatment of acne in patients aged 9 years and older. Altreno contains 0.05% tretinoin, in line with previous cream and gel formulations. The main difference between Altreno and previous forms of tretinoin is that Altreno is a lotion. Altreno may cause less skin irritation… Read More

Mini-Pulse Dexamethasone For Vitiligo

Vitiligo is an autoimmune disease in which the body’s immune system attacks the cells that produce pigment. The disease can remain localized, effecting a limited area, or may sometimes be progressive. Most currently available treatments, such as topical steroids or Excimer laser, address lesions that have already formed, but cannot prevent new areas of vitiligo… Read More

Qbrexza Approved For Hyperhidrosis

Qbrexza (glycopyrronium) cloth has been approved by the for the treatment of underarm sweating, also known as axillary hyperhidrosis. This medication is classified as an anticholinergic and works by interfering with the neurotransmitter that communicates with sweat glands. It is related to the oral medication glycopyrrolate, which has long been used for hyperhidrosis. One cloth… Read More

Dupilumab for Atopic Dermatitis

Dupilumab (brand name Dupixent) is shaping up to be a game-changer in the treatment of atopic dermatitis, often referred to informally as “eczema”. Dupixent addresses an underlying immune dysregulation that contributes to the development of atopic dermatitis. It blocks IL-4 and IL-13, two important cytokines in the TH2 pathway. In a clinical trial, after 12… Read More