Prurigo nodularis is a challenging problem to treat. It manifests as nodules in the skin, secondary to chronic scratching, and underlying pruritus (itch). Prurigo nodularis has been treated with a wide range of medications and treatments, including topical steroids, antihistamines, mirtazapine, gabapentin, phototherapy, and cyclosporine with variable results. Two recent case study reports indicate that… Read More
Dupilumab for Atopic Dermatitis
Dupilumab (brand name Dupixent) is shaping up to be a game-changer in the treatment of atopic dermatitis, often referred to informally as “eczema”. Dupixent addresses an underlying immune dysregulation that contributes to the development of atopic dermatitis. It blocks IL-4 and IL-13, two important cytokines in the TH2 pathway. In a clinical trial, after 12… Read More
